Immune Disorders

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Biology of the Immune System

• Overview of the Immune System
  • Components of the Immune System
  • Lines of Defense
    • Physical barriers
    • White blood cells
    • Molecules
    • Lymphoid organs
  • Plan of Action
    • Recognition
    • Activation and mobilization
    • Regulation
    • Resolution

• Innate Immunity
  • Monocytes and Macrophages
  • Neutrophils
  • Eosinophils
  • Basophils
  • Natural Killer Cells
  • Mast Cells
  • Complement System
  • Cytokines

• Acquired Immunity
  • Lymphocytes
    • T cells
    • B cells
  • Dendritic Cells
  • Antibodies
    • IgM
    • IgG
    • IgA
    • IgE
    • IgD
  • Strategies for Attack

• Effects of Aging on the Immune System
  • Newborns
  • Older adults

• Immunotherapy
  • Cytokines and Cytokine Receptors
  • Fusion Proteins
  • Monoclonal Antibodies

Allergic Reactions and Other Hypersensitivity Disorders

• Overview of Allergic Reactions
  • Causes
  • Symptoms
  • Diagnosis
    • Skin testing
    • Allergen-specific serum IgE tests
    • Provocative testing
  • Prevention
    • Environmental measures
    • Allergen immunotherapy (desensitization)
  • Treatment
    • Antihistamines
    • Mast cell stabilizers
    • Corticosteroids
    • Other medications
    • Emergency treatment
    • Treatment of allergies during pregnancy and breastfeeding

• Anaphylactic Reactions
  • Causes
    • Anaphylactoid reactions
  • Symptoms
  • Diagnosis
  • Treatment
  • Prevention

• Angioedema
  • Acute angioedema
  • Chronic angioedema
  • Symptoms
  • Diagnosis
  • Treatment
    • Emergency treatment

• Hereditary and Acquired C1 Inhibitor Deficiency
  • Symptoms
  • Diagnosis
  • Treatment
    • Emergency treatment
    • Medications to prevent attacks of angioedema

• Autoimmune Disorders
  • Causes
  • Symptoms
  • Diagnosis
  • Treatment
    • Medication treatment
    • Plasma exchange and intravenous immune globulin
  • Prognosis

• Exercise-Induced Allergic Reactions
  • Diagnosis
  • Treatment

• Food Allergy
  • Other reactions to food
  • Causes
    • Alpha-gal syndrome
    • Oral allergy syndrome
    • Eosinophilic gastroenteropathy
  • Symptoms
  • Diagnosis
  • Treatment
    • Other medications for food allergies
    • Allergen immunotherapy (desensitization)
  • Prevention

• Mastocytosis
  • Types of mastocytosis
  • Symptoms
  • Diagnosis
  • Treatment

• Physical Allergy
  • Causes
  • Symptoms
  • Diagnosis
  • Treatment

• Allergies to Drugs
  • More Information

• Seasonal Allergies
  • Symptoms
  • Diagnosis
  • Allergy testing
  • Treatment
    • Nasal symptoms
    • Eye symptoms
    • Allergen immunotherapy (desensitization)

• Year-Round Allergies
  • Symptoms
  • Diagnosis
  • Allergy testing
  • Treatment
    • Eye symptoms
    • Allergen immunotherapy (desensitization)
    • Surgery
  • Prevention

Immunodeficiency Disorders

• Overview of Immunodeficiency Disorders
  • Causes
    • Primary immunodeficiency
    • Secondary immunodeficiency disorders
    • Immunodeficiency in older adults
  • Symptoms
  • Diagnosis
    • History
    • Physical examination
    • Tests
  • Screening
  • Treatment
    • Preventing infections
    • Treating infections
    • Replacing missing parts of the immune system
  • Prevention
  • More Information

• Ataxia-Telangiectasia
  • Symptoms
  • Diagnosis
  • Treatment
  • More Information

• Chédiak-Higashi Syndrome
  • Symptoms
  • Diagnosis
  • Treatment
  • More Information

• Chronic Granulomatous Disease (CGD)
  • Symptoms
  • Diagnosis
  • Treatment
  • More Information

• Chronic Mucocutaneous Candidiasis
  • Symptoms
  • Diagnosis
  • Treatment
  • More Information

• Common Variable Immunodeficiency (CVID)
  • Symptoms
  • Diagnosis
  • Treatment
  • More Information

• DiGeorge Syndrome
  • Diagnosis
  • Treatment
  • More Information

• Hyper-IgE Syndrome
  • Symptoms
  • Diagnosis
  • Treatment
  • More Information

• Hyper-IgM Syndrome
  • X-linked hyper-IgM syndrome
  • Autosomal recessive hyper-IgM syndrome
  • Diagnosis
  • Treatment
  • More Information

• Leukocyte Adhesion Deficiency
  • Symptoms
  • Diagnosis
  • Treatment
  • More Information

• Selective Immunoglobulin A (IgA) Deficiency
  • Symptoms
  • Diagnosis
  • Treatment
  • More Information

• Selective Antibody Deficiency With Normal Immunoglobulins
  • Diagnosis
  • Treatment
  • More Information

• Severe Combined Immunodeficiency (SCID)
  • Symptoms
  • Diagnosis
  • Treatment
  • More Information

• Spleen Disorders and Immunodeficiency

• Transient Hypogammaglobulinemia of Infancy
  • More Information

• Wiskott-Aldrich Syndrome
  • Symptoms
  • Diagnosis
  • Treatment
  • More Information

• X-Linked Agammaglobulinemia
  • Symptoms
  • Diagnosis
  • Treatment
  • More Information

• X-Linked Lymphoproliferative Syndrome
  • Symptoms
  • Diagnosis
  • Treatment
  • More Information

• ZAP-70 Deficiency
  • More Information

Transplantation

• Overview of Transplantation
  • Donors
  • Organ Matching and Distribution
  • Pretransplantation Screening
    • Tissue matching
    • Donor screening
    • Recipient screening
  • Suppression of the Immune System
  • Pregnancy and Transplantation
  • Complications After Transplantation
    • Rejection
    • Infections
    • Cancer
    • Atherosclerosis
    • Kidney problems
    • Gout
    • Graft-versus-host disease
    • Osteoporosis and stunted growth
    • Donor complications
  • More Information

• Heart Transplantation
  • Donors
  • Procedure
  • Complications
    • Rejection
    • Transplant-related atherosclerosis

• Kidney Transplantation
  • Donors
  • Procedure
  • Complications
    • Rejection
    • Cancer

• Liver Transplantation
  • Donors
  • Procedure
  • Complications
    • Rejection
    • Hepatitis
    • Other complications

• Lung and Heart-Lung Transplantation
  • Donors
  • Procedure
  • Complications
    • Infections
    • Poor healing
    • Rejection

• Pancreas Transplantation
  • Donors
  • Procedure
  • Complications
    • Rejection

• Pancreatic Islet Cell Transplantation
  • Procedure
  • Complications

• Small Intestine Transplantation
  • Procedure
  • Complications
  • Rejection
  • Graft-versus-host disease
  • Other complications

• Stem Cell Transplantation
  • Procedure
  • Stem cells from blood
  • Stem cells from bone marrow
  • To recipient
  • After the stem cell transplantation
  • Complications
    • Infections
    • Graft-versus-host disease
    • Recurrence of the original disorder

• Transplantation of Other Tissues
  • Skin
  • Cartilage
  • Corneas
  • Bone
  • More than one tissue
  • Other tissues