Nonsteroidal Anti-inflammatory Drugs (NSAIDs)

NSAID

Usual Dosage (Oral)

Maximum Recommended Daily Dose

Nonselective NSAIDs

75 mg 2 times a day or 50 mg 3 times a day

100 mg once/day sustained-release

150 mg

300–500 mg 2 times a day

1200 mg

300–600 mg 4 times a day

3200 mg

100 mg 2 or 3 times a day 

300 mg

400–800 mg 4 times a day

3200 mg

25 mg 3 to 4 times a day

75 mg 2 times a day sustained-release

200 mg

50–75 mg 4 times a day

200 mg once/day sustained-release

300 mg

Meclofenamate

50 mg 3 or 4 times a day

400 mg

7.5 mg once/day

15 mg

1000–2000 mg/day in 1 dosage or in divided dosages (500–1000 mg 2 times a day)

2000 mg

250–500 mg 2 times a day

1500 mg

1200 mg once/day

1800 mg

20 mg once/day

20 mg

150–200 mg 2 times a day

400 mg

400 mg 3 times a day

1800 mg

Cyclooxygenase-2 (COX-2) selective NSAIDs

200 mg once/day or 2 times a day

400 mg

* COX-2 specificity is unclear.