Some Causes of Acute Pancreatitis

Cause

Examples

Medications

ACE inhibitors, asparaginase, sulfa medications, valproate

Infectious

Coxsackievirus B, cytomegalovirus, mumps, hepatitis A, hepatitis E

Inherited

Multiple known gene mutations, including a small percentage of patients with cystic fibrosis

Mechanical/structural

Gallstones, endoscopic retrograde cholangiopancreatography (ERCP), trauma, pancreatic cancer or periampullary cancer, choledochal cyst, sphincter of Oddi stenosis, pancreas divisum

Metabolic

Hypertriglyceridemia, hypercalcemia (including hyperparathyroidism), estrogen use associated with high lipid levels

Toxins

Alcohol, methanol

Other

Cigarette smoking, pregnancy, postrenal transplant, ischemia caused by hypotension or atheroembolism, tropical pancreatitis

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