Overview of Osteopetroses

Osteopetroses can be categorized based on whether sclerosis or defective skeletal modeling predominates. There are a number of different types, including

• Craniotubular dysplasias

• Craniotubular hyperostoses

• Osteosclerosis

They are all familial but have different inheritance patterns. Some types are comparatively benign; others are progressive and fatal.

Bony overgrowth sometimes severely distorts the face. Malocclusion of the teeth may require specialized orthodontic measures.

Plain x-rays typically are diagnostic.

Surgical decompression may be required to relieve elevated intracranial pressure or to release a trapped facial or auditory nerve.