Causes of Renal Cortical Necrosis
Patient Group | Causes |
|---|---|
Neonates | Placental abruption (causes about 50% of cases) Congenital heart disease (severe) Dehydration Fetomaternal transfusion Perinatal asphyxia Renal vein thrombosis |
Children | Dehydration |
Pregnant and postpartum women | Pregnancy complications (cause > 50% of cases among women): Placental abruption, amniotic fluid embolism, intrauterine fetal death, placenta previa, preeclampsia, puerperal sepsis, uterine hemorrhage Sepsis (causes about 30%) |
Others | Burns Disseminated intravascular coagulation Drugs and medications (eg, nonsteroidal anti-inflammatory drugs) Hyperacute renal allograft rejection Incompatible blood transfusion Nephrotoxic contrast agents Poisoning (eg, phosphorus, arsenic) Trauma |
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