Differentiating Staphylococcal Scalded Skin Syndrome (SSSS) and Toxic Epidermal Necrolysis (TEN)
Feature | SSSS | TEN |
|---|---|---|
Patients affected | Infants, young children, and adults who are immunocompromised | Older adults |
Patient history | Recent staphylococcal infection | Medication use |
Level of epidermal cleavage (blister formation)* | Within the granular cell (outermost) layer of the epidermis | Between the epidermis and dermis or at the level of the basal cell |
* Determined by Tzanck test or by a frozen section of a fresh specimen. | ||
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