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Grade	Description
Minimal	Changes at bite site only No systemic symptoms or signs or abnormal laboratory findings
Moderate	Changes extending beyond the bite site Non–life-threatening systemic symptoms and signs (eg, nausea, vomiting, paresthesias) Mildly abnormal coagulation or laboratory changes without clinically significant bleeding
Severe	Changes involving the entire extremity Severe systemic symptoms and signs (eg, hypotension, dyspnea, shock) Markedly abnormal coagulation and laboratory changes with or without clinically significant bleeding
Data from Lavonas EJ, Ruha AM, Banner W, et al. Unified treatment algorithm for the management of crotaline snakebite in the United States: results of an evidence-informed consensus workshop. BMC Emerg Med. 2011;11:2. Published 2011 Feb 3. doi:10.1186/1471-227X-11-2