Causes of Interstitial Lung Disease
Category | Examples |
|---|---|
Systemic rheumatic disorders | Ankylosing spondylitis (rare) Behçet disease (very rare) |
Medications and illicit drugs | Selected list: |
Genetic disorders | Fabry disease (rare) Familial pulmonary fibrosis Gaucher disease (rare) Hermansky-Pudlak Syndrome Niemann-Pick disease (rare) Pulmonary alveolar microlithiasis |
Idiopathic interstitial pneumonias | Cryptogenic organizing pneumonia Desquamative interstitial pneumonia Idiopathic pleuroparenchymal fibroelastosis Lymphocytic interstitial pneumonia Nonspecific interstitial pneumonia Respiratory bronchiolitis–associated interstitial lung disease |
Occupational and environmental exposure | Inorganic (selected): Aluminosis (caused by exposure to metallic aluminum powder), asbestosis, baritosis, beryllium disease, coal workers’ pneumoconiosis, exposure to hard metals (eg, cadmium, cobalt, titanium oxide, tungsten, vanadium carbides), radiation fibrosis, siderosis, silicosis Organic (selected): Bagassosis, bird fancier’s lung, coffee worker’s lung, farmer’s lung, hot tub lung, humidifier lung, malt worker’s lung, maple bark stripper’s lung, mushroom worker’s lung, tea grower’s lung (see Hypersensitivity Pneumonitis) |
Vasculitis | Eosinophilic granulomatosis with polyangiitis Giant cell arteritis (rare) Granulomatosis with polyangiitis Polyarteritis nodosa (rare) Takayasu arteritis (rare) |
Miscellaneous disorders | Chronic aspiration Eosinophilic pneumonia, acute and chronic Lipoid pneumonia |