Astragalus

ByLaura Shane-McWhorter, PharmD, University of Utah College of Pharmacy
Reviewed/Revised Jan 2023
View Patient Education

Astragalus, a perennial plant that is native to China, Mongolia, and Korea, has been used for centuries in traditional Chinese medicine. It is commonly combined with other herbs and used for many conditions.

(See also Overview of Dietary Supplements and National Institutes of Health (NIH): Astragalus.)

Claims

Astragalus is said to be useful for many conditions, including upper respiratory infections, allergic rhinitis (hay fever), asthma, chronic fatigue syndrome, and chronic kidney disease.

It is also said to strengthen the immune system and prevent physiologic and psychologic stress.

Astragalus is used topically to improve blood flow and speeding wound healing.

Evidence

There are no high-quality studies in people demonstrating that astragalus is effective for treating any health condition (see NIH: Astragalus).

1).

Adverse Effects

Adverse effects from astragalus are uncommon, but rash, itching, nasal symptoms, or stomach discomfort may occur.

Astragalus might make the immune system more active, which can worsen the symptoms of autoimmune diseases such as rheumatoid arthritis and systemic lupus erythematosus.

Astragalus should not be used during pregnancy or while breastfeeding. Animal studies suggest that astragalus can be toxic to the mother and fetus.

Drug Interactions

Astragalus may interact with medications that suppress the immune system. Astragalus may increase immune system activity and thereby may decrease the effectiveness of medications that suppress the immune system, such as those used after organ transplant or to treat cancer.

(See also table Some Possible Dietary Supplement–Drug Interactions.)

Reference

  1. 1. Zhang HW, Lin ZX, Xu C, Leung C, Chan LS: Astragalus (a traditional Chinese medicine) for treating chronic kidney disease. Cochrane Database Syst Rev (10):CD008369, 2014. Published 2014 Oct 22. doi:10.1002/14651858.CD008369.pub2

More Information

The following English-language resource may be useful. Please note that THE MANUAL is not responsible for the content of this resource.

  1. National Institutes of Health (NIH), National Center for Complementary and Integrative Health: General information on the use of astragalus as a dietary supplement

Drugs Mentioned In This Article

quizzes_lightbulb_red
Test your KnowledgeTake a Quiz!
Download the free Merck Manual App iOS ANDROID
Download the free Merck Manual App iOS ANDROID
Download the free Merck Manual App iOS ANDROID